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Differences among these three species, however, may also partially be due to the coverage and sequence quality of the genomes.> Most of the protein sequences, which have high sequence identity with those well-described protease in MEROPS database, were confirmed as having a conserved protease-specific domain (Additional file 1).
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The blinding process remained complete until all data was entered in the trial database and the accuracy of the data and the database was confirmed.
Validity of the database was confirmed by checking against reference lists provided by local experienced researchers in orthopaedic outcomes.
The identities of the compounds proposed by Adam and NIST98 databases were confirmed with retention times and spectra of co-injected synthetic reference compounds.
The pORFs with significant matches to these reference databases were confirmed as genes, while the pORFs that overlapped with them from a different reading frame (the shadow pORFs) were deemed spurious pORFs.
Although MEDLINE identified about 62% of all citations and 76% of electronic citations relevant for this review, sources of data other than the major electronic databases are confirmed to be crucial.
Thirteen IPs in this database that were confirmed on serology tests for antibodies to the virus do not have estimated infection dates; we assume that these IPs were infected 10 days before reporting, which is the period suggested by DEFRA in the database.
Thirty-five (38.9%) of the 90 case-patients in the case database had contacts listed in the contact database; 25 (71.4%) were confirmed and 10 (28.6%) had probable cases.
Compounds common to all or most AG seed samples were compared to the Wiley 7th Edition/NIST 05 mass spectral database, and identifications were confirmed by coinjection with authentic standards on both nonpolar and polar columns and by identity of unknown and standard mass spectra.
Of the 350 700 possible host pest combinations in the database, 15 328 (4.37%) were confirmed host records for a pest; we assumed (conservatively) that the rest were incompatible interactions.
Novel mutations not reported in the database of COSMIC were confirmed by Sanger sequencing or pyrosequencing as described previously [ 12].
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