In order to find out if the core 70 or 91 variants might be linked to the phylogeny HCV-1b, core sequences from the 9 patients included in this study and 100 randomly chosen database sequences were compared by phylogenetic tree analysis.
Treatment information recorded in the Trent study database was compared to that inferred by patterns of repeat HCV RNA testing.
Therefore, the predicted proteolysis activity analysed by the BIOPEP database was compared with the SEC chromatograms of AHEPVK and GPSMR in the current study.
IGRs containing candidate sRNA loci were compared by BLAST to a database of all IGRs.
Suspicious reference sequences were compared by BLAST against NCBI non-redundant nucleotide database and removed from the reference database.
Spacers were compared by NCBI BLASTN against the nr and env_nr nucleotide databases.
The two resulting databases were compared and discrepancies resolved by referring back to source data.
Group means were compared by factorial ANOVA.
Htt levels were compared by chemiluminescence densitometry.
Proportions were compared by Chi-square analysis.
