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Comparison of the A1180V carrier frequency between our studies and the results of dbSNP database was tested by using the Fisher's exact test.
The integrity of the database was tested by examining the adjusted risk of hypoglycaemia of antidiabetic drugs and insulin, which was consistent with our general knowledge (Tables S12 S14).
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Storage of molecules in the database is tested by comparing a molecule restoredfrom the database with the original molecule.
The database is tested by ADEFC and variable length genetic algorithm-based fuzzy clustering (VGAFC) techniques for finding optimal number of clusters automatically.
The reliability of the thermodynamic database was tested in two quaternary model cast alloys by comprehensive comparison of their experimentally measured solidified microstructure characteristics and phase transition temperatures with the calculated ones.
Overrepresentation of gene sets defined by the KEGG database was tested using the Fisher's exact test.
The ability of the calibration to compensate for attenuation, scatter and partial volume losses, which is the foundation of the harmonisation process, was tested by comparison of databases before and after its application.
Up-regulation detected by the initial screenings was tested by qRT-PCR in a broader database of unrelated dogs.
The decoy database was generated by Mascot (www.matrixscience.com) in the following way: during the search, every time a protein sequence from the target database is tested, a random sequence of the same length is automatically generated and tested.
Significance was tested by the permutation test.
Normality was tested by Kolmogorov-Smirnov test.
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CEO of Professional Science Editing for Scientists @ prosciediting.com