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The database was refined in a series of steps, using newly acquired sequence data at each stage.
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Because the MetaFlux component of Pathway Tools generates constraint-based models directly from the EcoCyc PGDBs, as the database is refined through new curation, those refinements are automatically incorporated into newly generated versions of the model.
In order to analyze homogenous schools, the original PISA databases were refined.
The extraction program of the Canning Flu Tool was refined initially with a mock database and later with a real patient database.
Afterwards, this database that consisted of 310732 unique entries was refined by applying a physicochemical property-based filter.
The assembly was refined where possible using homology to the SwissProt database to indicate contig accuracy.
Subsequently, the STITCH compound-protein interaction dataset was refined to only consider compounds that were FDA-approved drugs (as classified in the DrugBank database).
The process eventually was refined.
And the marketing was refined.
It was refined.
Chemotherapy was refined.
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