Conserved Ath-Lincs were blasted (local BlastN) against the NCBI-database to assess whether the sequences were conserved in other organisms.
Additionally, we analysed the interactions between the variables and databases to assess whether the effect of the variables on the outcomes differed significantly between databases.
We used the PHARMO database to assess antihypertensive drug use.
In designing the interrogation tool it was decided from the outset to include all episodes of AF and not to make any attempt based on database interrogation to assess whether susceptibility to AF might have resolved.
Our primary goals were to estimate the frequency of strain replacement ("successful superinfection") in the Virolab and EuResist collaborative European databases, and to assess whether superinfection contributes to virologic failure due to acquired drug resistance.
Using a cell proliferation assay, compounds from a National Cancer Institute (NCI) database were tested to assess whether they suppressed the growth of the wild-type cell line [ 53].
Sequence completeness was assessed using Full-Lengther v0.15 [ 72], which uses a combination of BLAST searches against UniProt and the NCBI non-redundant (NR) database, and ORF prediction to assess whether transcripts contain the entire protein coding region.
Lack of data of previous admissions outside of the Pediatric Health Information System database limited our ability to assess whether this cohort's outcomes were better, no different, or worse than those of the included children.
In this study, we used data from the NLCA database from 2004 to 2010 to assess whether there has been a temporal change in the overall survival.
Because it is a B73-specific database, we were not able to assess whether luxurians-specific TEs or repeat families may have contributed to an increase in the luxurians genome size.
With the growing number of automatically generated databases containing chemical structures derived from patents, it seems timely to explore ways to assess whether these databases are fit for purpose and to compare them in a fair and systematic manner.
