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These samples are submitted to UC Davis Veterinary Genetics Laboratory for DNA testing, where the database is housed, and the DNA is analyzed and the Canine CODIS database searched for corresponding profiles.
In contrast, the Rd.HMM score is insensitive to the size of the database searched (not shown).
The protein sequences were used in both protein-protein, position-specific iterated and translated BLAST searches (using default parameters) depending on the database searched (http://www.ncbi.nlm.nih.gov/).nih.gov/
Due to handsearching in various journals done by the Cochrane Collaboration, a number of non-English papers not included in other databases are part of the database searched for this project [23].
Statistical significance inference from RAId_aPS only depends on the total number of qualified peptides inside the database searched but is not dependent on the peptide content inside the database.
We can then safely conclude that the Rd.HMM from X-ray resolved protein structures are highly selective, and the number of relatives present in the sequence database searched did not affect this selectivity.
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The database searches for possible suspects.
Peaks due to keratin contamination were excluded from database searching.
Database searching identified 3580 citations.
Thirty-six studies were identified through database searching.
The initial database searching identified 5,062 articles.
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