In contrast, for the SITW database, the reduction in SIA was from 82.5 to 53.33%.
For the TIMIT database, the reduction in SIA was from 90% at 30 dB to 39.17% at 10 dB.
The vision transcends national legislation, policy, and local languages, and it creates a supranational virtual population, whose seat of life is not in the organism but in the database, resisting reduction to existing local, biological, and legal forms of life.
The RP15 (threshold 15%), RP35, RP55 and RP75 sets yield a database size reduction of 53, 45, 37 and 30%, respectively, with respect to the source sequence set (of complete proteomes).
The approach is similar to algorithms used in tools for database complexity reduction (Li et al., 2001).
Using the 3- vs. 4-tiered score developed from the present database, a reduction from 40 to 31% can be achieved.
As the actual dose of cetuximab was not consistently available in the database, dose reduction was determined through analysis of cetuximab payments and defined as a decrease in payment of at least 10% between successive cetuximab claims.
Reference database size reduction is achieved through the use of genetic markers storing only the more informative sequences (Berendzen et al., 2012; Liu et al., 2011; Segata et al., 2012).
Linkage with other healthcare and demographic databases enabled reduction of potential confounding through statistical techniques as well as adjustment for competing risks of mortality, as many men with prostate cancer are known to die of other causes.
Likewise, for the SITW database the SIA reduction was from 80.83 to 66.67% for 30and 0 dB, respectively.
