To begin with, as depicted in Figure 2, several SNPs exhibited an inverse distributional profile compared to available databases on other populations, such as the Caucasians or Chinese (see DMET Supplementary Data in Supplementary Material available online at http://dx.doi.org/10.1155/2015/542543).org/10.1155/2015/542543
Both databases can be used in combination to verify hypotheses, to cross-check a finding with one database on the other, or to train a mathematical model on one data set and to test it on the other, thereby avoiding the issue of overfitting.
Alternatively, database depositors can port pre-existing databases built on other platforms onto BioSlax, and save the difference as an LZM Slax module file that includes everything changed from the base LiveOS.
To determine whether a putative PAS obtained analyzing one database ("examined database") was annotated as a PAS on other database ("validating database"), all transcripts in the validating database that had a PAS in the same position as the PTE were considered.
However, the counter argument is that the expected benefit from population-wide forensic DNA database, on the other hand, will impact on the balance between privacy rights of the individual and society needs for security, leading to a "surveillance society" (Zadok et al. 2010).
In a hypothetical Zsyntax-based database, on the other hand, the simple search with the keywords "TP53 & MDM2" (where & is our non-Boolean Z-conjunction) in the initial aggregate would return all of the theorems involving these two molecules in their exact molecular context.
The Reaxys database, on the other hand, contained a total of 51 out of 1362 possible isomers or 3.7%.
In addition, the similarity of the results in the different trial populations, capturing MTX-naïve patients with early RA on the one hand (rituximab database) and patients across all lengths of disease duration and prior drug experience (golimumab database) on the other, was highly confirmatory and clearly adds to the generalisability of our findings.
The openSputnik database, on the other hand, has extra information available, including the ESTs flagged as low quality and excluded from the analysis in this report, a number of supplementary BLAST fields, and UniGene functional annotations based on mappings of Swissport and InterPro to GO [ 54].
Its open-data nature, together with its ancillary information, will facilitate comparative analysis, as will the growing availability of databases focusing on other aspects of the rich animal diversity, and tools to query and combine them.
