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Sequence alignment analysis of the CFTR exon 9 homologous sequences revealed that five registered mutations in the Cystic Fibrosis Mutation Database may be due to the undesired annealing of primers to a homologous sequence, resulting in inappropriate PCR amplification.
The particular sensitivity to such noise when applied to the NIST 2008 database may be due to the natural characteristics of the interview speech.
The low overlap between our predicted genes and DrugBank database may be due to the relatively small number of known disease-related enzyme genes.
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One view is that the high percentage of retained intron (RI) events observed in plant EST databases may be due to contamination from genomic DNA or from incompletely processed nuclear RNA.
We demonstrate evidence that high discriminability between preictal and interictal intracranial electroencephalogram (iEEG) recordings [1,2] of the Freiburg database (FSPEEG) may be due to the amount of time that occurred between recordings, as opposed to the underlying seizure state, i.e., preictal or interictal.
Differences between the predicted and reported (e.g. literature, databases) gene relationships may be due to differences among the experiments considered (e.g. honey bee versus fruit fly) and insufficient or inaccurate information (e.g. small experiment, limited microarray platform).
Differences between this study and earlier evaluations may be due to improved database performance over time, possibly due to competition between databases.
That inconsistency may be due to the database because these studies based on clinical datasets or register.
The chitinase activity of A. faecalis MOR02 may be related to a chitin deacetylase protein found in the COG database, whereas the activity on Tween 80 may be due to the presence of lipases/esterases.
On the other hand, the geographic gap in Russia may be due to the databases selected, urging for an integration of Asian boreal forest data in future studies.
We have acknowledged that the heavy reliance on field studies and subjective measures may be due to existing databases not capturing the dynamism of the Asian or Chinese context or because they are incomplete.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com