Conclusions In this series of population based case-control studies in two large primary care databases, exposure to bisphosphonates was not associated with an increased risk of common gastrointestinal cancers.
This study has combined cohorts from 13 countries, consisting of 98,665 workers (2,110,913 person-years), and included the development of a comprehensive database of exposure measurements for the retrospective assessment of study participants' exposure (Kauppinen et al. 1997, 2002).
Paprotny, D., Morales Nápoles, O. & Jonkman, S. N. HANZE: a pan-European database of exposure to natural hazards and damaging historical floods since 1870.
The information on statin therapy was extracted from the claims database, and exposure time was estimated for each patient based on the amount of statin continuously received by the patient, reported as person-years.
They concluded the extent of information loss from unmapped records and the challenging data structure of THIN limited their CDM's usefulness for pharmacoepidemiological research, primarily because of database drug exposure and condition loss.
Formaldehyde is a well-studied chemical and effects from inhalation exposures have been extensively characterized in numerous controlled studies with human volunteers, including asthmatics and other sensitive individuals, which provide a rich database on exposure concentrations that can reliably produce the symptoms of sensory irritation.
Selection of scale is perhaps the most important factor in creating and analyzing GIS databases for exposure assessment and epidemiology.
This assessment was guided by the scientific and technical literature, consultation with experts, and a review of existing databases of exposure assessment.
The exposure-based assessment has been carried out for only these three risk factors because they were the only ones with both a method for quantified estimation of health impacts and global databases of exposure assessment available.
The first set, the Arsenic Occurrence and Exposure Database, or AOED, consisted of a compilation of state compliance-monitoring databases, included only 25 states (whose monitoring the EPA thought suitable) with different reporting limits.
