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The ChEMBL database constituted a source of active and inactive compounds with experimentally verified activity towards selected targets.
Each query protein was compared using a reciprocal best BLASTP hit to the database constituted of the four proteomes and classified in one of the 15 possible categories.
Therefore, TBLASTN was performed to search the translated nucleotide database constituted of the different studied genomes using the proteomes as queries [ 37].
Finally, a custom database constituted by bacteria, fungi, virus and protozoa (source: NCBI Reference Sequence, RefSeq, March 2014) was used as reference to align the reads of each sample.
To test this, we performed a four way comparative genomic analysis on a database constituted of H. sapiens, S. cerevisiae (representatives of Opisthokonta), A. thaliana (Plantae) and E. histolytica (Amoebozoa) proteomes to identify the proteins that are specifically present in Opisthokonta and divergent/absent in Plantae and in Amoebozoa.
In addition, the presence of genomic clusters in the D. solani and D. dadantii species was searched with a nucleotide BLAST analysis using the sequences of the specific clusters as queries against a database constituted by the D. solani and D. dadantii genomes (e-value threshold = 10-50).
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On Thursday, the attorney general of Massachusetts filed an objection on behalf of his state and the others in the bankruptcy court, asserting that the sale of the database constitutes an unfair and deceptive trade practice.
Carefully curated and reviewed by experts in multiple disciplines, the database constitutes a valuable resource for developing and validating structural alerts for drug-induced human liver injuries.
In the proposed method, the K distinct subjects or classes within the face database constitute a random sample from a large population of face classes.
The optimisation through systematic variation and the structured parameter documentation in a database constitute the scope of the prospective research building upon the present paper.
The database constitutes a major resource for those conducting research or looking for information on large magnitude explosive eruptions from around the world as it synthesises data from a wide range of sources.
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