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The applicability range methodology can be extended beyond the database analyzed in the present work to any study that needs to use one value to represent a population with broad variations and limited knowledge of the underlying distributions.
The database analyzed in this study included details of ICU admissions between 2009 and 2012.
The database analyzed in this study includes details of all ICU admissions between 1989 and 2002, including demographic factors, admission diagnosis, admission source, severity of acute illness as measured by APACHE II scores based on the worst first 24-hour ICU data [15], daily organ failure assessment and supportive therapy required [16], and ICU and hospital survival outcome.
The database analyzed in the present study is provided as additional material (see additional file 1: database,.csv format).
This can be partly attributed to the microsatellite search criteria and the characteristics of the EST database analyzed in these studies.
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A list of microarray databases analyzed in the present study.
Staging of the tumors in all the databases analyzed in this study also varies significantly (Table 1).
From examination of the Mus musculus and Rattus norvegicus databases, analyzed in Table 1, it is clear that they contain less positive sequences than negative sequences (upstream region).
DC designed the database, analyzed the data and assisted in writing.
Each patient's next of kin was informed, and written consent was obtained with the understanding that routine clinical and monitoring data were to be collected, stored in a database, analyzed for research purposes, and possibly published (once rendered anonymous).
To assess whether the patterns of sequence variability observed for clade B (Figure 1) apply to other clades, the entropy for available clade A1, C, and D HIV-1 complete protein sequences in the LANL HIV Sequence Database were analyzed in parallel for Shannon entropy at each amino acid position.
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