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To identify genes that function in specific biologic pathways, these 3,538 genes were further filtered using functional annotations derived from the NetAffx database‚ Analysis Center (Liu et al. 2003; http://www.affymetrix.com/analysis/index.affx), together with manual annotations from published literature, before hierarchical clustering using GeneSpring.
Data related to preoperative medical history, physical exam, and instrumented three-dimensional gait analysis were extracted from a historic database in a motion analysis center.
We extracted all gene probe sets from the U95Av2 microarray that were involved in the purine pathway (n=103), cell cycle regulation (n=561), apoptosis (n=407) or repair (n=192), based on the NetAffx™ analysis center database (http://www.affymetrix.com).
This research has made use of the National Aeronautics and Space Administration NASAA)/Infrared Processing and Analysis Center (IPAC) Extragalactic Database (NED), which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA.
Completed case report forms were submitted via dedicated facsimile to the ACORN analysis center and entered into a secure database.
If the annotation for interested genes were missed in the gene database of GenMapp, they were examined in Affymetrix NetAffya analysis center [ 61].
Participants consented to protocols approved by the local Human Investigations Committees at both the University of North Carolina Chapel Hill and Duke University Medical Center and were recruited from a database maintained at the Duke-UNC Brain Imaging and Analysis Center and by flyers posted in campus and medical center locations.
The department then sent a picture of the suspect to the Maryland Coordination and Analysis Center, which combed through one of the nation's largest databases of mug shots and driver's license photos in search of a match.
This map was downloaded as a single CSV file from the NetAffx analysis center in July 2009 [55], and is based upon reference-sequence similarity from the HomoloGene database [56].
The institutional review board of the Sheba medical center approved this study on the basis of strict maintenance of participants' anonymity during database analysis, accordingly no individual consent was obtained.
Design: Observational database analysis.
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