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They used a wide variety of approaches: biomarker selection based on biologically sensible hand-fit models or highly data-driven trial-and-error models.
For data driven trials and research, a data set obtained from an experimental intelligent inhabited environment has been used as a benchmark system.
We therefore pursued a data-driven index of single-trial dynamics from LFP data.
A case study may feel less data-driven than a medical trial or a scientific experiment, but attention to rigor and valid methodology remains vital.
He's also used his leverage to push the philanthropic world to become more data-driven, advocating for randomized control trials of charitable projects.
However, the adaptive two-stage design implemented in this trial allows a data-driven modification of the sample size of the second stage based on the results of the interim analysis or on external information while the specified significance level is controlled when the decision rules defined above are adhered to [ 35].
The last issue is proposed by Pocock et al.[ 23] for avoiding misuse and data-driven selection of covariates within the clinical trial setting.
204 Readers will likely draw weaker inferences from a trial that was truncated in a data-driven manner versus one that reports its findings after reaching a goal independent of results.
Drawing on data-driven presentations from several focused meetings, this paper synthesizes lessons from past microbicide trials and provides recommendations for future trials of microbicide and other HIV prevention technologies.
We introduce a new data-driven approach (PrOCTOR) that directly predicts the likelihood of toxicity in clinical trials.
63, 64 A group of laboratories from academia and industry have embarked on an effort to provide a data-driven reproducible methodology for dystrophin quantification that could be used in future trials.
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