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2) The LGN immunostaining data would be greatly improved by the addition of a control staining on LGN -/- cortical sections.
Present data, and the arguments we have presented based on this data, would be greatly strengthened if autopsy follow-up of patients with AD or FTD with high plasma TDP-43 values were available.
Active surveillance studies conducted in rural settings using routinely collected data would be greatly improved by overall health system strengthening, including better diagnostic capacity, nominal vaccination registers (or other methods by which to verify individual vaccination status), and electronically collected data for ease of processing and analysis.
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Clearly, data extraction would be greatly facilitated in electronic medical records.
The systematic use of such experimental data for model refinements would be greatly facilitated by the development of computational methods assisting the curator with his task, however.
The perceived value of OTC sales as a data source for syndromic surveillance would be greatly enhanced if it could be shown that OTC sales provided an earlier indicator for health problems than could be obtained from clinical data.
Including this information in future analyses would be greatly beneficial.
It is clear that expandability of the workflow would be greatly facilitated if data files were standardized to make them universally readable.
Without the Front-End Optimization (FEO), which streamlines both the number of HTTP requests and the size of the data, speed for loading and opening webpages would be greatly diminished.
Although not necessary, the paper would be greatly strengthened by CryoEM data with CPX. 8.
It would be greatly beneficial if narrative patient data and causality were incorporated into a timeline.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com