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If necessary, a redistribution of data will be performed internally.
Logarithmic transformation of the data will be performed where appropriate.
Analyses of the data will be performed using multilevel models.
Double entry of data will be performed in Epidata [ 27].
Analysis of the activity data will be performed using Actilife program (v5, MTI, Pensacola, USA).
The analysis data will be performed by independent professionals blinded to the assignment group.
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Follow-up periodical analyses of ASHIP-data will be performed to monitor the impact of varicella and herpes zoster vaccination in Germany.
Data monitoring and data management will be performed by the independent Trial Coordination Center (Appendix G).
Data analysis will be performed by the data management and analysis center, using SAS/STAT® software.
Anonymous data extraction will be performed at the data storage centre.
Data storage will be performed in accordance with local data protection laws.
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