Early-stage samples were taken from patients with stage I, IA, and IB cancers, whereas late-stage data were obtained from stage III and IV patients.
Staging data were converted from the International Federation of Gynaecology and Obstetrics (FIGO) 1988 to the FIGO 2009 staging system [ 28] according to individual patients' pathology reports.
Patients with missing stage data were excluded from the analyses.
Viral load, the prescription of ART and HIV staging data were abstracted from medical records.
Transcriptome data were generated from three stages of the C. owczarzaki life cycle (Sebé-Pedrós et al. 2013), with three replicates produced for each stage, and are available in the NCBI BioProject PRJNA20341.
No prospective randomised clinical trials have directly compared carboplatin and carboplatin/paclitaxel in this setting; however, data were available from 120 stage 1 patients enrolled into the ICON3 trial [ 14] (supplementary Appendix, available at Annals of Oncology online).
Data were collected from L4 stage animals except where otherwise noted, and all experiments were performed at 25°C because this elevated temperature enhanced the neuronal defects in the ptrn-1 mutants (data not shown), except for those shown in Figure 7B F, which were performed at 20°C.
Lymph node-level data were parsed from Collaborative Stage site-specific factors 3 and 4 of the SEER data for H&N tumor site, which included information regarding lymph node involvement for levels 1, 2, and 3 and levels 4, 5, and retropharyngeal lymph nodes, respectively.
The database searches yielded 4691 papers that were assessed for inclusion in the review and after the screening and verification stages data were extracted from 52 papers that described intervention studies to address health literacy and lifestyle risk factor modification provided by different health professionals, see Figure 1 for PRISMA [ 31] flow chart.
Moreover, the present data were derived from patients with severe COPD GOLDD stage III) and thus cannot be applied to the overall population of patients with COPD.
