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Data were interrogated using content analysis (Berelson and Lazarsfeld 1948), selected due to its broad applicability, well-established nature and particular utility in structuring and systematising documentary analysis (Bryman 2001; Reason and Garcia 2007).
TOF/TOF fragmentation data were interrogated using FlexAnalysis software and analyzed against a theoretical peptide digest using Protein Prospector.
The data were interrogated using the Clinical Record Interactive Search CRISS) application, 19 with a robust anonymisation process and patient-led oversight.
Cumulative branch distribution data were interrogated using the Kolmogorov Smirnov test, n > 5. Larvae were rapidly dissected in cold PBS to remove the fat bodies and subsequently frozen.
Data were interrogated using Mascot version 2.2 (Matrix Science, UK) against the UniProt database (version 2011-05) witaxonomyofy of Homo sapiens selected.
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Therefore, spectral data was interrogated using principal component analysis to assess whether it could be used to unambiguously identify a polymer type in a sample regardless of its age, formulation or the presence of additives and plasticisers.
The resulting mass data was interrogated using an offline version of the MASCOT search engine (Matrix Science) using the SPtrEMBL database with the following search criteria: allowance of 0 or 1 missed cleavages; peptide mass tolerance of 50 ppm; trypsin as digestion enzyme; carbamidomethyl modification of cysteine; methionine oxidation as partial modification; and charged state as MH+ [ 14].
Brain (striatum) gene expression data were obtained using the Illumina Mouse WG 6.1 array, and the data sets were interrogated using a weighted gene co-expression network analysis (WGCNA).
Data sets were interrogated using the Ingenuity Pathways Analysis (IPA) application (Ingenuity® Systems, Redwood City, CA; http://www.ingenuity.com).com
Cells were interrogated using a FACScan flow cytometer (BD Biosciences, San Jose, CA) with data acquisition using CellQuest (BD Biosciences) or a LSR-II flow cytometer (BD Bioscience) with data acquisition using DIVA software (BD Bioscience).
Suspects were interrogated using methods such as waterboarding, slapping, humiliation, exposure to cold and sleep deprivation.
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