The correlation of normalized read counts between biological replicates in the ChIP-seq data was further assessed using the DiffBind Bioconductor package (Stark and Brown, 2011).
Agreement between MWS and NSHD data was further assessed by the intraclass correlation coefficient, ICC 1,1) in the notation of Shrout and Fleiss [ 35].
During eligibility assessment and data extraction, trial records for which data were ambiguous were further assessed by DG.
Associations between number of admission days and significant data among the two groups were further assessed by single factor linear regression.
Full-text articles were further assessed and data were entered into a prespecified table including 12 entry fields (see online supplementary appendix 3).
Full-text articles were further assessed and data were entered into a prespecified table that included information on authors, year of publication, sample size, type of DPP-4 inhibitor, duration of follow-up, comparator drug, baseline HbA1c and outcomes.
Studies that met our stated criteria were further assessed for the requisite data, and when possible, similar outcome data were combined to generate frequency-weighted means.
Genome regions that demonstrated statistically significant associations with dsDNA status were further assessed using the 450 k methylation data.
The size effect of any genetic flow, if observed, could be further assessed by simulating data under different models and comparing simulated data summaries with the observed data.
