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Haplotypes within the sibships in the ascertained family data were established using the SimWalk2 software [15], based on the available information about the parental HLA genotypes.
Distance trees of the nucleotide sequence data were established using the following parameters: i) 572 characters, ii) distance measure = LogDet/paralinear, iii) ties were broken at random, iv) 1000 bootstrap replicates were used for statistical analysis.
Because some marker names were ambiguous, connections between markers in the linkage and RH data were established using primer sequence.
The data were established using the free software EpiData Association version 3.1 (http://www.epidata.dk/download.php) and cross-checked with double entry.
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Normal distribution of data was established using D'Agostino-Pearson normality test.
The statistical significance of the data was established using the two sample student's t-test.
Including all measurements, correlations between data pairs were established using linear regression analysis and are expressed as the square of Pearson's correlation coefficients (r).
Including all consecutive hemodynamic measurements per patient, correlations between data pairs were established using linear regression analysis and are expressed as the square of Pearson's correlation coefficients (r).
The corresponding data structure and database were established using the object-oriented method in the Visual C++ environment.
Models were established using data obtained with the steady-state spatially resolved probe (41 samples) and the Y-shaped optical probe (28 samples).
Reliability and validity of the CAPE were established using data from a longitudinal study involving 427 children with physical disabilities [ 27].
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