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To create synthetic data we have avoided committing an "Inverse Crime" [ 27].
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Since filters of the data may affect individual datasets differently, we have avoided using them in order to reflect the true unbiased gene expression signatures.
If we had a CDO a year ago could we have avoided the loss of the Post Office data file?
"We have avoided recessionary measures".
But we have avoided Spain, Italy, England.
We have avoided excessive exclusion criteria.
We have avoided a systematic review.
We are convinced that we have carefully interpreted, and not over-interpreted, the data presented and have avoided any overstatement.
Prospective data collection could have avoided this problem.
Following many analyses of these data we have truncated the data to avoid this problem.
However, the approaches suggested to date have generally focused on conversion of gene expression data to discrete states and have avoided the use of formal statistical methods for quantifying the joint density of the resulting parameters.
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