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Final analysis of the DICOM data was completed using Dolphin 3D (version 10.5, Dolphin Imaging, Chatsworth, CA, USA).
Analysis of the fMRI data was completed using statistical parametric mapping (SPM5; http://www.fil.ion.ucl.ac.uk/spm).ac.uk/spm
Hierarchical clustering of protein data was completed using average linkage clustering, and visualized using Cluster and TreeView software, respectively (http://rana.lbl.gov/EisenSoftware.htm).htm
Statistical analysis of final data was completed using SPSS 19.0.
Network analysis of the microarray data was completed using the Ingenuity Pathway Analysis software [ 50].
Data was completed using Statistical Package for Social Sciences (SPSS) software version 16.0.
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The correlations of the experimental data were completed using the Wilson-HOC, NRTL-HOC and UNIQUAC-HOC models.
For repeated measures, missing data were completed using the last observation carried forward (LOCF) method.
The data were completed using metabolic databases - mainly Metacyc [ 24], KEGG [ 22] -.
Missing data were completed using information from the redundant markers of the contiguous assembly.
In those patients with missing values, data were completed using multiple imputation methods.
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