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Data were assessed for quality and relevance.
For data analysis, raw data and the normalized probeset data were assessed for quality using the 'aroma.affymetrix' package in R [ 23] and Expression Console from Affymetrix [ 24].
Data were assessed for quality according to a set of criteria based on the OECD TG 305E bioconcentration test protocol (OECD 1996).
The raw sequence data were assessed for quality using FASTQC software (http://www.bioinformatics.bbsrc.ac.uk/projects/fastqc/) and aligned to the mouse reference genome MM9 (build 37) using TopHat (Langmead et al., 2009; Trapnell et al., 2009).
Data were assessed for quality and then imported into GeneSpring GX7.3.1 and pre-processed by using robust multiarray averaging (RMA) followed by normalization of each probe to the median of all samples.
The raw data was assessed for sizing quality using GeneMapper v4.0 (Applied Biosystems, Germany).
Midterm data were assessed for reliability of catch-up growth, resulting quality of atrioventricular valves, and adequacy of 2-ventricle repairs.
Costs and quality of life data were assessed for missing data.
Quality controlled, digitized sequence data were assessed for TDR using the Stanford HIV Database.
Before statistical comparisons can be made, the data must be assessed for quality and normalisation procedures must be applied, of which many have been proposed.
These data have not been assessed for quality (Howard PH, personal communication).
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