Sentence examples for data to the annotation from inspiring English sources
We used HMMSplicer [ 58] to compare junctions revealed by our data to the annotation provided by Vectorbase and Ensembl [ 33, 60].
By comparing the sequence coverage data to the genome annotation, 20 non-annotated regions were found to have significant transcriptional activities.
They did this by looking for matches from the input read data to the gene annotations from the green lizard (Anolis carolinensis); this being the closest species to snake that has a full set of genome annotations.
Therefore, the establishment of a proteomic reference map for this strain in the free-living state can both add valuable protein-expression data to the genomic-annotation process [ 21– 23] and help to attribute probable functions to hypothetical proteins [ 21, 23].
Before analyzing gene expression across tissues, the two sexes and the female gonotrophic cycle, we utilized our sequencing data to update the annotation of protein-coding genes in the Ae. aegypti genome (Fig. 2d).
Through a proteogenomics effort, we have used MS/MS data to anchor the annotation of previously undescribed genes and to re-annotate previous gene models in order to improve the current genome annotation.
As a final step in our analysis, we used our proteomics data to improve the annotation of other Yersinia genomes.
The low number of reactions in the reconstruction as compared to similar models like E. coli and Salmonella is the result of a reduced set of metabolic pathways in this organism and of limited legacy data to confirm the annotation of its genome.
If this option is enabled (disabled by default), our current algorithm adds novel exon-exon junctions detected from the RNA-seq data to the supplied transcript annotations.
A comparison of the 12 novel genes proposed by proteomics data to the refined STM14028 genome annotation revealed 9 of the 12 novel genes were also identified and annotated similarly in the refined annotation (Additional file 1 Table S4B).
We compared our aligned data to the eight empirically-determined annotation tracks as previously mentioned.
