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The controversy surrounding the original article reflects the need for data to be reproduced by multiple labs before potential therapies such as bexarotene gain momentum as a panacea for AD.
Currently the implemented compromise algorithm is to require the regulatory relationship identified by expression data to be reproduced in at least one of the two other experiments: ChIP-chip and RNAi.
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This comprehensive grading system, utilising currently available knowledge, illustrates a progressive approach and while the data have yet to be reproduced elsewhere, its clinical merit warrants further inspection.
The underlying goals of data publication are to enable research to be reproduced and data to be reused.
The '-omics' data sometimes are difficult to be reproduced which are mainly due to biological variations and variation of 'capture time slot' of the samples [ 69, 70].
18 While these data are highly encouraging, they need to be reproduced in a well‐powered trial.
We define reproducibility as the ability of an entire experiment to be reproduced [ 16], from data acquisition to results.
If the quality of data is known to be low, data might be reproduced by repeating necessary reactions.
Some critics say that for the test to be accepted, the Lancet data must be reproduced by others and the technique tested in larger trials.
The fact that ground magnetic data cannot be reproduced well by current MHD models supplying boundary conditions to AMIE has also been discussed (Ridley et al. 2001).
"It's whether the data can be reproduced by others consistently.
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