To study the necessity of data points-in-time, the mean absorbed dose for each kidney per administered activity (D/A administered) was determined when omitting one of the data points (1 h, 1 day, 2 days, or 7 days) and compared with D/A administered based on data from all time points.
Assuming the number of data points in time is N, and the number of features is m, then the feature space is of dimension N-by-m.
For each gene remaining in the table, the expression level averaged over all remaining data points in time was calculated.
Second, the process of tracking itself, by generating a series of data points in time, enabled the building of knowledge of the history of a patient's condition and pattern recognition in terms of trends or sudden changes.
Peak latencies and peak amplitudes were measured as the most positive or most negative data point in a time window.
From this final dataset of 1494 proteins and 4904 transcripts, two proteins and two transcripts contained a negative data point in their time series profiles, and were removed from both mother and daughter datasets in subsequent analyses.
Second, since an entire set of observations is used to compute every coefficient, the uncertainty associated with that coefficient may be small even if the uncertainty on each individual data point in the time series is fairly large.
Figure 3b depicts a Sakoe Chiba band [16] that prevents pathological warping paths, where a data point in one time-series sequence matches too many data points of another as in Fig. 1b.
Let be the number of simulated mRNA data points in each time interval between time points t j and (i.e.e).e
(3) When the difference exceeded the empirically determined outlier threshold of 100 ppb, the data point in the measured time series was marked as an outlier.
