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However, data on the responsiveness of the ASUI scores requires further research.
Thus, the effect of the missing data on the responsiveness rankings would be minimal.
There were no published data on the responsiveness of these outcome measures.
For future research, additional data on the responsiveness to interventions, such as the start of TNF blockers, have to be established.
None of the authors of the included instruments provided data on the responsiveness of their instruments (i.e. the extent to which the instrument measures physician change over time).
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Additional file 1: This file contains a graph with data on the dose responsiveness of the reactivation effect caused by the complexes as Figure S1.
For the FAOS no information on the responsiveness is available.
Although the clinical effects of inhaled GCs vary, there are few data on the differences in the responsiveness of individuals to inhaled GCs.
N/A: Information is not available in publications in French or English None of the instruments provided data on their responsiveness (i.e. the extent to which it measures change within a physician over time).
Data on airway responsiveness over the first for 4 weeks following randomization were available for 28 participants.
We will collect data on the reliability, validity and responsiveness of these modified questionnaires concurrently with the trial analysis.
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