More details on the implemented data structures, their worst-case time complexities, and the chaining algorithm can be found in the Additional file 1.
Then, the existing RA [11] has been extended (step 4) and evaluated (step 6) based on new empirical data gathered from the implemented architecture (step 3).
To correct for baseline differences in demographics, the data on PA was implemented in the Chronic Disease Model per age subgroup 50-64 yearss, >64 years) and gender subgroup.
Since consultation was basically offered to all patients, data on the treatment actually implemented are not available in a relevant proportion of those who presented for consultation but were not treated at the IPC.
Therefore, a template based on the chronic care model was developed for the collection of data on various interventions implemented within the disease management programs to improve care for chronically ill patients.
The efficacy of individual measures for the prevention of VAP is well documented, and data on the impact of implementing bundle measures have usually been reported from studies in which several measures are implemented simultaneously in the general intensive care unit (ICU).
In addition, data on the process of implementing a change and the context will be collected both by questionnaire and individual interviews.
Data on the impact of implementing the IADPSG criteria are currently based on retrospective analysis comparing the two-step screening strategy or the former WHO criteria with the IADPSG criteria.
However as there is no empirical data on the impact of implementing different mixes of interventions for control of helminths - Plasmodium falciparum co-infections, rigorous community based efficacy and feasibility studies have been recommended for any integrated control strategy in order to inform on the best practices that will improve the quality of life in primary schools [ 16, 37- 41].
Additional information including data on the cost of implementing the software program, differences in the utilisation of resources in and outside the hospital, labour costs and the total readmission reduction opportunity available to patients in different risk groups is needed to establish the cost-effectiveness of the intervention.
