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Some doctors say the short-term data on statin use in children is reassuring and mirrors long-term safety data in adults.
Doctors who sat on the academy's committee on nutrition, which issued the guidelines, agree there are no long-term data on statin use in children.
After five years, more than a third of the men in both groups were taking statins, but no further data on statin use was available after that.
We illustrate the graphical assessment of the potential impact of an additional study on an existing meta-analysis using published data on statin use and the risk of acute kidney injury.
Follow-up data on statin use were available until February 2008.
Data on statin use during admission was available for 188 patients.
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The clinical studies evaluating statins and bone effects have been from observational cohorts of women taking statins or from data obtained from randomized, controlled clinical trials with information on statin use and fracture endpoints.
Although data were not available on statin use in this cohort, a growing body of experimental evidence exists describing a synergism between cisplatinum and statins in vitro [ 35- 37].
We had complete and independently collected data on preadmission statin use and one-year mortality, which limited the risk of information and surveillance bias.
Data on statin prescription use from a national pharmacy claims database were used to determine whether or not patients achieved 120 day adherence.
We used a simulation framework introduced by Setoguchi and colleagues based on real-world claims data modeling statin use [20].
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