Based on the data suggesting a role of peripherin in axonal outgrowth and our findings discussed above, we propose that the binding of peripherin to CMT2B-causing RAB7A mutants alters peripherin functions thus affecting neurofilament dynamics and as a consequence neurite outgrowth and axonal regeneration.
On the other hand, emerging data support a role of serotonin (5-HT) in the rewarding effects of psychostimulants [2].
Thus, on the basis of recent data suggesting a role of adjuvant imatinib therapy in terms of improving recurrence-free survival after the resection of primary localized GIST, the patient was placed on imatinib [ 24]; he is alive and well a year after the second operation.
Data on a protective role of fumarate in acute ischemia of the rat heart led to the obvious hypothesis that addition of fumarate to the preservation solution for kidney transplantation may have beneficial value.
Nowadays, there are few data on a potential role of fructose in the progression of CHC.
The PubMed searched yielded 84 randomized controlled trials (RCTs) and 36 meta-analyses or systematic reviews, indicating a consistent bulk of data on the role of BoNT-A for the treatment of chronic pain.
Here we present data on the role of a host-cell encoded protein, PSIP1/LEDGF/p75, that guides integration site selection by lentiviruses, the viral genus including HIV (henceforth we use "LEDGF/p75" because this name is widely used in the HIV field).
Our own preliminary data on receptor involvement suggest a role of EP3 receptor, which expression is significantly upregulated on the addition of 10 pg/ml PGE2 to OA articular cartilage explants (E.V. Tchetina, J. DiBattista, A.R. Poole, unpublished data).
Although there is ample epidemiologic evidence that PM10 and PM2.5 play a role in asthma, there is a paucity of data on the role of ultrafine PM in asthma.
Although a growing area of interest, there remains a lack of data on the role of sociocultural norms and practices on newborn healthcare-seeking in sub-Saharan Africa and the extent to which these norms can be modified.
