Nucleosome positioning data of resting CD4+ T cell was obtained from [ 45].
The nucleosome occupancy data of resting CD4+ cell are get from one publication [ 24].
So far, the ability to meaningfully use fMRI data (that is, data of resting-state as well as task-related fMRI) on a single-subject level has been very limited.
> The data of resting whole saliva, chewing-stimulated whole saliva and acid-stimulated whole saliva are presented as mean values with standard deviations in Tables 3 and 4. >> The mean resting whole saliva and acid-stimulated whole saliva, 0.2 (SD = 0.2) and 1.2 (SD = 0.9) ml/min, respectively, were somewhat above the hyposalivation cut-off values.
Task-based connectivity: The procedure described in the previous paragraph was applied to task-based data instead of resting state data.
The inherent advantage to this approach is that whole-brain data analysis of "resting state data" effectively circumvents many of the methodological pitfalls associated with examining "activation" changes in clinical samples (e.g., task difficulty, performance inequalities) (see [12], [15]).
Here, approaches range from taking the gradient (a) throughout the data range of resting to Maximal Voluntary Contraction (MVC), (b) tangents at individual data points, (c) linear regressions at discrete force levels ((b) and (c) being 'reference standard' as they utilise a number of distinct regions of the Force Elongation Relationship (FER)).
In the following two sections the nucleosome data of human resting T-cells from Schones et al. [ 6] was used.
This procedure enabled a recording of a complete data set of resting (photophase) and activity (scotophase) during a period of 24 consecutive hours.
Preprocessing and ReHo process were using the software DPARSF Data Processing Assistantt for Resting-State fMRI. http://www.restfmri.net), a MATLAB toolbox for 'pipeline' data analysis of resting-state fMRI [ 43, 44].
