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However, these data need to be considered with caution.
Once a design is selected, and data obtained from it, models for representing the data need to be considered and fitted.
Lastly, it follows that any small-molecule inhibitor bound to Ca2+ S100B would also have to cause an increase in calcium-ion-binding affinity to be effective therapeutically inside a cell, so these data need to be considered in future drug design studies involving S100B.
The description of 3D objects is aimed at skeleton modeling, surface modeling, inner modeling, and property modeling, and thus geological data need to be considered as much as possible (González-Garcia and Jessell 2016), including cores, outcrops, logs, seismic data, test data, boreholes, maps, and so on (Bourdeau et al. 2017).
The questionnaire data need to be considered with caution for two reasons.
These omics data need to be considered in the context of the cellular processes to achieve their full potential.
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Which unintended consequences might occur due to the availability of this data needs to be considered before making such data publicly available.
Consequently, most information in this review is from studies rated at unclear risk of bias, and the proportion of studies at high risk of bias for missing outcome data needs to be considered when interpreting the results (Additional file 1: Figures S5a and S5b).
Therefore, the observed discrepancy between self-report and objectively (e.g. chemically) validated behavioural data needs to be considered when drawing conclusions from self-report findings.
As such, this data needs to be considered within the context of those limitations.
At the same time, the diversity and heterogeneity of the data sources need to be considered in order to properly retrieve needed data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com