There has been a major weakness in lack of data in terms of quantitative exposure assessment and cancer cases; these data are necessary to enable adequate detection of the excess risks, and thus it is a logical presumption that previous findings could be somewhat underestimated.
Therefore, further analysis, repartition and harmonisation of the data are necessary to enable a more valid comparison of intakes across Europe.
Improved data are necessary to enable Ireland to incorporate nurse migration into "the overall workforce planning approach" [ 43] and in order to move away from the perception of international nurse recruitment "as a cheap option with 'expendable' migrant health professionals" [ 43].
Integrated analysis of these diverse data types is necessary to enable a full understanding of the mechanistic events driving metabolomic changes.
To profile AMI on a national level from routine hospital and mortality statistics, data linkage is necessary to enable systematic analysis of person-based disease occurrence to be undertaken.
Finally, none of the approaches supports dynamic processing (transformation) of the exchanged data, which is often necessary to enable the proper usage of data by a target tool.
Indeed, a minimum level of compliance with data sharing risks is necessary to enable the scientific value of the platforms.
While the CDEs can be used to tag individual files it is not clear yet how much metadata is necessary to enable automatic data extraction (e.g. extract properties for a single frame from a time series) and processing, and if such metadata can be extracted directly from the files without user input.
In order to evaluate and use data sources by the OTN users, it is necessary to enable metadata querying of all registered datasets.
These data identified the 5T4 transmembrane domain as sufficient and necessary to enable CXCR4 cell surface expression and chemotaxis.
Due to the complexity of interaction data already available in the public domain, this aim proved impossible to achieve, with a rewrite of version 1.0 proving necessary to enable all this information to be expressed within the interchange format.
