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Some other methodological limitations must be noted: The quality of data might be limited due to different interviewers and settings and due to missing data on health state in 24 of the 136 children.
However, the depth and amount of the data might be limited.
As a result of the not randomized study design, the representativeness of the data might be limited.
Analysis of the presented data might be limited by partly incomplete documentation as well as the individual interpretation.
Because a high number of patients in Europe are being treated outside such centers, the generalizability of data might be limited.
For other outcomes like the assessment of refusal skills, validity of self-report data might be limited by restricted accessibility, that is, whether adolescents are really able to judge their own competence to resist cigarette offers.
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In particular, it could be used for endangered species for which the availability and/or sequence data might be limiting and the possibility to study immortal cell lines could give new information on genome organization and function relevant for their preservation.
As a consequence, the use of standard sensitivity analyses for BIA data set might be limited because of the lack of appropriate distributions as data sources are limited, or because of the need for forecasting.
In the configuration presented in Figure 2B,C the activity range of the NOT gate is almost fully covered by OUTPUT1, but for low OUTPUT1 values the activity is already decreasing; this effect can make the estimation of transfer function parameters difficult in real experiments, where the number of data points might be limited.
However, the accuracy of real-time ionospheric products on a global scale might be limited by data availability, as the public real-time data stream is currently more concentrated in certain regions, i.e., North America, Europe, and Australia.
This implies that comparing the data for RPE or CR-10 might be limited to homogeneous groups based on aerobic fitness levels [ 21, 23– 27], training status [ 3, 13, 26– 29], or healthy aged people [ 30, 31].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com