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Of note, data on the length of storage were available for only 66% of the patients.
Data on the length of storage were available for 296 of 447 (66%) transfused patients.
Demographic data for transfused patients for whom length of storage data was documented are shown in Table 1.
Furthermore, these missing data did not allow us to analyze the data according to other RBC length of storage cutoffs due to sample size issues.
Daily data collection included RBC transfusion events, length of storage of RBC units, MODS variables, clinical information and complications.
Data were analyzed in transfused patients with recorded length of storage according to the oldest RBC unit length of storage per patient.
Data regarding the indications for blood transfusion and length of storage of RBCs were not available, therefore prohibiting any inference about RBC storage and clinical outcomes.
The confidence intervals (CIs) of storage times at each actual age overlapped such that there was no significant influence of the length of storage time on classification accuracy (data not shown).
These novel and important observational data justify undertaking a randomized controlled trial to evaluate the effect of RBC length of storage on the outcome of critically ill children.
Definitive conclusions cannot be drawn, but these observational data justify undertaking a randomized controlled trial to evaluate the effect of RBC length of storage in critically ill children.
There were no significant differences when comparing the demographic data and severity of illness at admission of patients for whom at least one RBC length of storage was documented (n = 296) and those for whom no length of storage was recorded (n = 151).
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