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Limitations: The number of patients excluded from the study due to missing data is substantial.
Allison ([2002]) demonstrated that even in the case of MCAR, dummy-variable adjustment may lead to biased estimates in ordinary least squares regression when the proportion of missing data is substantial (i.e., 50%).
However, the effort required to compile and process these detailed data is substantial, and presents a major barrier to more widespread adoption.
However, the discrepancy between the accuracy of IDEM as assessed by synthetic data vs. real expression, methylation and knockdown data is substantial.
However, given that the amount of imputed data is substantial, we can never completely rule out the possibility of remaining bias caused by differences in the unobserved/unmeasured characteristics that are also associated with FPG at follow-up.
If the proportion of missing primary data is substantial (more than 10%) a series of sensitivity analyses will be carried out to determine the likely effects of missing data [ 99- 101].
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The committee's concerns over wholesale collection and analysis of data were substantial and from any perspective would need considerable changes to be made to the draft bill, now presented as an amendment to the Counter Terrorism and Security Bill.
Even with this limited data (the Internet was one-way at the time; all we could look at were "clicks") and the limitations of computing power, the value created from the data was substantial.
Figure 2 shows the Secchi depth during June to August in the Gulf of Finland since year 1900, and regression analysis, a t-test and a non-parametric test all showed that the Secchi depth has decreased significantly over time, although the variability of the data was substantial.
The resources required to determine true cases from those diagnosed in BCBST claims data were substantial.
Both the last observation carried forward and multiple imputation techniques will be considered if missing data are substantial.
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CEO of Professional Science Editing for Scientists @ prosciediting.com