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It is worth noting that pooled estimates from logged and un-logged data in trials of surgical patients are similar and are the same in mixed and medical ICU populations.
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Despite almost routine collection of PRO data in clinical trials of AEDs and the wide choice of PRO instruments, PRO results are not being routinely reported on European Medicines Agency (EMA) and Food and Drug Administration FDAA) product labels.
Despite collection of patient reported outcome (PRO) data in clinical trials of antiepileptic drugs (AEDs), PRO results are not being routinely reported on European Medicines Agency (EMA) and Food and Drug Administration FDAA) product labels.
The purpose of this model was to provide a way to derive utilities from the micturition diary data, which are usually collected in trials of OAB treatments.
As it stands, it is unclear as to whether the problem of the poor reporting of harms data in trial publications is a result of the lack of awareness of the CONSORT for harms statement, or journals and peer reviewers not implementing this guideline.
Both Sharp and Larsen scores have been used to report outcome assessment data in clinical trials of TNF antagonists.
Although we examined three common sources of multiplicity of data in trial reports, there are other types of multiple data in trial reports for example, different types of analysis such as intention to treat and per protocol analyses.
Objectives To examine the extent of multiplicity of data in trial reports and to assess the impact of multiplicity on meta-analysis results.
Authors of systematic reviews should anticipate and consider the multiplicity of data in trial reports when writing protocols.
Multiplicity of data in trial reports might lead to biased decisions about which data to include in meta-analyses and hence threaten the validity of their results.
2 There is often a multiplicity of data in trial reports that makes it difficult to decide which ones to use in a meta-analysis.
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