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These data highlight the usefulness of mapping disease susceptibility loci using a transancestral approach, particularly in a region as complex as the MHC, and offer a springboard for further fine-mapping, resequencing and transcriptomic analysis.
These data highlight the usefulness of proteomic analysis as a complement to conventional analytical methods for thorough analysis of proteolytic events elicited by calpain.
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The data highlights the usefulness of yeast as a model system to unravel intraspecific natural genome diversity and to elucidate how natural selection shapes the yeast genome.
These data highlight the limitations and clinical usefulness of the MRC-SS as a marker of ICU-AW in a general ICU population in the early stages of critical illness.
These data also highlight the usefulness of having 1 center that deals with unusual infections, where expertise in diagnosis and management can be built up and maintained.
The included studies all assessed the impact of different approaches to Indigenous identification on health outcome estimates and highlight the usefulness of data linkage for exploring the impact of minority under-identification in routinely-collected health data.
Together with our data in murine CIA, these findings highlight the usefulness of targeting the EGFR family in RA.
Our results highlight the usefulness of next-generation sequence data for investigating expression profiles in the genome as well as in specific candidate genes.
Our study's goal was to highlight the usefulness of providing cost-effectiveness information alongside comparative effectiveness data that reflect routine clinical practice on representative patients, so we did not extrapolate beyond our data.
The findings highlight the usefulness of combining gene expression patterns and epigenetic data to identify tumour biomarkers, and suggest that NDRG2 silencing might bear influence on tumour invasiveness, being associated with a more advanced stage.
While all of these studies highlight the usefulness of WES as a diagnostic tool, additional data are needed to inform both clinicians and payers about the appropriate clinical indications and diagnostic yield for WES.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com