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Recent compelling, yet limited data have determined that postmenopausal women who carry a functional polymorphism in the CYP2D6 gene have a worse clinical outcome than women who have a wild-type genotype.
For instance, Smith et al. [ 16] using simulated datasets on dichotomous data have determined that Type I error rates (defined here as the probability of falsely rejecting an item as not fitting the Rasch model) were significantly less than α = 0.05 for both infit and outfit mean squares using a range of critical values (0.7, 0.8, 0.9 – 1.2, 1.3, 1.3).
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"For example, some of the articles over time have said things like data has determined that if you're in a romantic scene, the guy should wear a green shirt, or something like that.
Prior risk models based upon epidemiology from predominantly the atomic bomb survivor data has determined that radiation-induced lung cancer has the greatest carcinogenic risk for solid tumors and this may be due to the number of cells at risk in the lung compared to other organs [ 17].
The company does not reveal when its systems were compromised; nor exactly when it discovered the intrusion; nor how long it took to launch an investigation — writing only that: "As part of a review of our systems and data, we have determined that there has been unauthorised access to certain data held by the company.
Using a combination of Serial Analysis of Gene Expression (SAGE) and Affymetrix GeneChip data we have determined that developing body wall muscle cells express a minimum of 4,430 genes (excluding ribosomal genes) [25], [26].
According to these data we have determined that the MIC of farnesol for P. brasiliensis is 25 μM, while the MLC is 30 μM.
On the basis of MAS NMR data, we have determined that WT VDAC and VDAC mutants S193E and S193A adopt similar structures when they are reconstituted in lipid bilayers.
Consistent with these data, we have determined that when liver-specific Xbp1-knockout mice in a C57BL/6J background are fed a high-fat/sucrose-fructose diet, they are more susceptible to develop progressive, fibrosing steatohepatitis with less steatosis than flox control mice.
However, Lidke et al. (unpublished data of our laboratory) have determined that ERK mutants unable to dimerize retain the ability to translocate to the nucleus, albeit at a slower rate.
Recent data from several groups have determined that moderate density CpG sequences have methylation features distinct from high density CpG islands, and thus may respond differentially to aging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com