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This possibility is not far-fetched: it has been suggested that translation initiation factors are localized at centrosomes [ 34– 36], and previous data has proposed that the mRNA binding protein, HuR, stores mRNA in the centrosome and that it controls de novo protein synthesis in near proximity to centrosomes via phosphorylation [ 36].
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Conflicting data have proposed that LC-uFFAs inhibit all major bacterial biosynthetic pathways within the cell, or alternatively, that they specifically inhibit FabI, which catalyses the final and rate-limiting step in fatty acid biosynthesis [12], [18], [22], [23].
Preliminary LOH data have proposed that allelic imbalance on 22q is more frequent in laryngeal and oral tumours than other HNSCC (dos Reis et al, 2002).
Preclinical data have proposed a role for PTEN loss and activation of the PI3K/AKT pathway in regulating androgen receptor (AR) transcriptional output and in driving resistance [5,12 14].
More current analyses based on high-throughput sequencing data have proposed a variety of heuristics for estimating genome size by identifying features in the k-mer spectrum [ 21] or by using arbitrary cutoffs in the k-mer spectrum [ 40].
However, there has been some good progress and, for example, both McCormack et al. (2013) with nuclear data and Gibb et al. (2013) with mitochondrial (mt) data have proposed a general group of "water carnivores" that includes Pelecaniformes, Ciconiformes (including storks), and some related groups but not the shorebirds (Charadriformes).
Recent development in privacy-preserving data mining has proposed many efficient and practical techniques for hiding sensitive patterns or information from been discovered by data mining algorithms.
From implications based on geophysical data, we have proposed a preliminary scenario of the generation mechanism of the 2011 Tohoku Earthquake.
Based on this data, we have proposed that the development of IBD requires three factors [1].
Based on our data we have proposed reliable diagnostic criteria for miscarriage (table 5).
Recent reports have evaluated the performance of gene expression normalization strategies when applied on aCGH data and have proposed more specific approaches [ 15, 16].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com