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34 The reliability of HIPE data has been documented.
The virtual absence of eEOCs in the postischemic kidney at 48 hours has been reported in previous eEOC/AKI-related studies [ 23, 33] and comparable data has been documented for mesenchymal stem cells as well [ 34].
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However, several limitations of these data have been documented, including a high percent of missing information and an underestimate of timing of the first prenatal visit and total number of visits [ 25].
Although recent findings have shown the presence of methylation and hydroxymethylation marks (5mC and 5hmC) in mtDNA by immunological and alternative methods, no data have been documented so far about this presence in DNA samples extracted from blood and cultured cells of humans and mice.
Interobserver variability in data collection has been documented in several studies [ 27, 28, 29].
The quality of Saskatchewan's administrative health data for research has been documented in multiple studies [ 9- 12].
The accuracy and completeness of Saskatchewan's administrative data for research has been documented in multiple studies [ 26- 28].
We thus found no correlation between TL and age of individuals (data not shown), as has been documented in other wild populations of long-lived species such as the kakapo Strigops habroptilus (a parrot; [ 13]).
The accuracy and comprehensiveness of the data recorded in the database has been documented previously.
Although the contribution of PTEN status to mTOR inhibitor sensitivity has been documented, data herein demonstrate that both PTEN-proficient and PTEN-deficient cells can be radiosensitized by mTOR inhibition.
Although concerns about the validity of longitudinal databases in primary care have been raised, the accuracy and completeness of the data recorded in the General Practice Research Database has been documented previously and the database is used extensively for health service and epidemiological research.
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