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The data generated support a mechanism of action involving proteasome activation by pyrazolones and provides insight into the potential of this chemical class in ALS therapy.
The data generated support the utility of this approach in defining quantitative changes that occur in a wide spectrum of low-abundance proteins, and they demonstrate consistent changes in TNF-α-regulated proteins, particularly in the patients who had the most robust clinical responses.
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Effectiveness data generated to support human development programs can be used to support the regulatory requirements for veterinary use.
Analysis of microbiology data generated in support of patient care by clinical laboratories across the United States has been used in the past to provide perspective on a variety of antimicrobial resistance trends among key bacterial pathogens [ 3- 6].
All summary or representative data generated and supporting the findings of this study are available within the paper.
Yale researchers are custodians of research materials and data generated with the support of Yale resources.
In contrast to the controversy over intelligent design versus Darwinian theory, here we find two theories that can be tested by experimentation and statistical analysis, and the data generated would objectively support or reject either hypothesis.
The validation process has been principally psychometric in nature, focusing on the reliability and validity of the data generated, with additional support coming from studies of the sensitivity and specificity of the measurement [ 2, 3].
The high capacity fileserver is capable of providing secure storage for all data generated by the supported projects at the MRRC.
The relevance of osteosarcoma as a model for a highly metastatic human cancer, along with preclinical data generated herein that supports the opportunity to evaluate mTOR inhibitors in canine osteosarcoma, paves the way for clinical evaluation of rapamycin and other mTOR inhibitors in tumor bearing dogs as part of an integrated and comparative drug development approach.
Data generated here do not support TNBC as a more aggressive disease in AAW.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com