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The accuracy in phase estimation of parental haplotypes was confirmed by genotype data from the offspring.
The accuracy in phase estimation of haplotypes for parents was confirmed by genotype data from the offspring.
Here we present a genotype-by-sequencing method for constructing a high-density genetic map using low-coverage, low-cost, whole genome sequencing data from the offspring of a wild cross.
The neonatal health data from the offspring in this trial did not raise any safety concerns associated with the use of quinagolide during the initial 3 weeks after OR.
Growth data from the offspring were collected at ages 6 months and 1 year from child welfare centers and at age 14 years by self-report from questionnaires mailed to the adolescents.
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It also required the use of a mathematical 'un-mixing' tool to separate the data obtained from the aging cohort from the data from the young offspring that the yeast produce while they age.
Data from the FHS offspring cohort exam [ 7] (1998-2001) were used for this comparative analysis.
Exclusion of data from these offspring resulted in a reduction in map size from 163 cM to 106 cM.
Since the southern Chinese group was familial related, the data from known offspring were excluded from the calculation of the carrier frequency to make sure the value was calculated from unrelated individuals (http://browser.1000genomes.org/Homo_sapiens/Variation/Population?db=core;r=3:38616415-38617415;v=r=31310765;vdb=var=3tion;vf=12532571).
Data from the prospective Framingham Offspring, Atherosclerosis Risk in Communities (ARIC), and Cardiovascular Health studies were pooled as previously described (5).
There was no significant difference in tool transfer frequency between mothers and offspring (Chi-square test for the pooled data from the three mother-offspring pairs: χ2 (1) = 0.21, p = 0.64).
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