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This means that a curator (a person tasked with manually managing data from submission through to its public release) will always review the information provided (whether it is a new submission or a suggested update) and decide whether it is suitable for immediate incorporation.
NCBI presented the flow of biological data from submission into the primary data archives, the steps taken during RefSeq curation, interactions with the community, annotation standards, application of pipelines and tools for validation and the interplay of human and machine curation.
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Logistic regression analyses demonstrated a strong relationship between the human and computed similarity assessments, with the resulting regression models having significant predictive power in experiments using data from submissions of orphan drug medicines to the European Medicines Agency.
We feel the new immunoFISH analysis of meiotic Tetrahymena chromatin that we include in our revised submission better resolves the localization of pericentric regions, and we will remove the mouse data from this submission as per the Reviewers' request (see revised Figure 7).
Data from specimen submission records, laboratory reports, and questionnaires were captured, combined, cleaned, and analyzed in a combination of Excel 2003 (Microsoft, Redmond, WA, USA) and EpiInfo v3.5.3 (Centers for Disease Control and Prevention, Atlanta, GA, USA).
The data from the submission have therefore been used The sponsor undertook either meta-analysis or quantitative synthesis on all key outcomes, which were compared with those of the conventional growth rod study [ 20] or the conventional rod arm of the case-matched study [ 19].
This is the first study to use surveillance data from laboratory submissions to describe the occurrence of PRRSV in Denmark.
These tables include gene variants with evidence scores of 7 or higher defined during the PhAESIS evaluation of each drug-gene pair (see Additional file 1: Sections 1 to 7 for abbreviated curated data from PAG submissions, including variant summary tables, genotype-phenotype interpretation Punnett squares, and PGx evidence for each of the approved drug-gene pairs).
It was somewhat surprising that the work of others was not mentioned and the data from this current submission not situated in the context of the studies by Sakaguchi and his colleagues (Ono et al (2007) Nature 446 685 689).
NIST evaluated our algorithm from submission data that was made using 44 hours of evaluation dataset.
Usually meeting notes and summary data from the original submissions were available; the full application was not usually available.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com