Sentence examples for data from multiple trials from inspiring English sources
Data from multiple trials have shown that patients who enter treatment with more severe cocaine withdrawal symptoms as measured by the CSSA scores do poorly (Kampman et al, 2001; Kampman et al, 2002; Mulvaney et al, 1999).
Use of these definitions at the FDA has enhanced the ability to aggregate data within and across medical product development programs, conduct meta-analyses to evaluate cardiovascular safety, integrate data from multiple trials, and compare effectiveness of drugs and devices.
By pooling data from multiple trials addressing the same or very similar thing, you generate the power of large numbers ― and can often replace suggestions about some association with some degree of statistical reliability.
For clinical trial data, meta-analysis of summary-level efficacy and safety data from multiple trials provides a quantitative framework for comparative efficacy and safety assessment.
When data from multiple trials are synthesized, such as in a meta-analysis, a negative study does not trump a positive study of similar quality.
With ever-larger trials, and meta-analyses of data from multiple trials, we have the statistical power to demonstrate quite small mean differences in these outcome measures that are unlikely to have arisen by chance.
Analysis of individual participant data enabled the most complete, detailed, and in-depth analysis and was not more resource intensive than extracting, collating, and analysing aggregate data from multiple trial publications and conference abstracts.
T-tests were applied in this case, as well as when comparisons were made between data sets pooled from multiple trials (repeated trials recorded in the same condition).
However, the result was consistent with data from multiple micronutrient trials in pregnancy; a meta-analysis of individual-level data from 12 trials showed an interaction between the allocation group and maternal BMI with a greater birth-weight effect in mothers of higher BMI in 11 of the trials (4).
Formulae to do this are uncommon because they require primary data from multiple randomized trials that measure both the surrogate and clinical outcome.
