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The result can be explained on the basis that all data from Evidence 1 had to be considered invalid resulting in an equivocal 50/50 probability that either hypothesis is true.
Jungreis I, Lin MF, Spokony R, Chan CS, Negre N, Victorsen A, White KP, Kellis M, 2011, Data from: Evidence of abundant stop codon readthrough in Drosophila and other metazoa (Genome Res. 2011 21: 2096-2113), http://genome.cshlp.org/content/suppl/2011/09/28/gr.119974.110.DC1/Data1_DmelReadthroughCandidates.txt, Freely available online through the Genome Research Open Access option (Supp Data1.txt ).
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There are no convincing or consistent data from evidence-based medicine that etomidate is associated with poor outcome, especially increased mortality, particularly if adjustment is made for pre-existing severity of illness.
We extracted and synthesised relevant data from the evidence to draft evidence-informed recommendations for rehabilitation.
Advocacy materials and presentations (APHRC 2005; NCAPD 2005) drew both from KDHS data and from evidence on the correlation between higher contraceptive prevalence rates, lower fertility rates, and increased maternal and infant survival published by UNFPA (2003).
All studies that satisfied the relevance criteria were included because there is an increasingly strong case for not excluding qualitative data studies from evidence synthesis based on quality assessment[ 1, 18, 19].
The data from the evidence matrix will be formatted to create a visual representation which facilitates interpretation.
The most common reason given for inclusion of case series data was the absence of sufficient data from randomised evidence to assess effectiveness or safety outcomes.
The process of combining data from the evidence synthesis and direct observations with feedback from various stakeholders is illustrated in Figure 2.
So according to these issues, the pooled results of the data from current evidence still need to be interpreted with caution.
For example, efficacy data from the EVIDENCE trial 66– 68 which lasted for 64 weeks was utilized in a model that simulated effects for a 4-year period.
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