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The MetaRanker 2.0 is a web-based gene prioritization tool in which several types of data from different genetic resources can be given as inputs.
The WT data was generated with r = 8 repeated measurements for each time point, whereas the KO data were simulated with only 4 repeated measurements for each time point (because each measurement includes data from different genetic contexts, see Methods).
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Notably, Lfng protein was easily detected in CD4+ T cells under all assay conditions as well as naïve CD4+ T cells from different genetic backgrounds (data not shown).
Soil samples were taken from different genetic horizons and their physicochemical properties were determined.
Mouse models from different genetic backgrounds often display variable phenotypes.
2) The data from the different genetic manipulations strongly suggests that there are different pools of UNC-49 defined by their differentially dependence on NLG-1 and FRM-3.
Hence, the collection of experimental data we worked with contained data from different interventions, genetic backgrounds and tissues.
As there are huge amounts of interaction data from different sources (genetic, proteomics) it is not easy to choose which gene/protein is the best candidate for further analysis in a complicated system like OXPHOS, which is composed of several complexes.
Second, we pooled the data from different ethnicities together, genetic heterogeneity among diverse ethnic populations leads to some unavoidable bias.
In this investigation, we excluded data from different groups associated with genetic discontinuities (see Methods) and instead focused on data from single lineages.
To do my work, I have to get genetic data from different parts of the world, and look at differences within groups and between groups, so it helps to have labels for groups".
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