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The data for the offspring sample are shown in Figure 3.
We used the negative binomial distributions fitted to the Ebola transmission data for the offspring distribution.
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The accuracy in phase estimation of haplotypes for parents was confirmed by genotype data from the offspring.
To additionally investigate whether the PCB-related reduction in birth weight is also detected when only considering one offspring per mother, we analyzed data for the first offspring born after 1968 (n = 89).
The data for each offspring from the GAII and the HiSeq2000 was combined for all further analysis.
The heritability of this quantity was investigated by regressing the child values against the mean of the parent values in HapMap trios for which microarray data were available for the offspring and both parents (56 trios).
Although very low birth weight and premature infants are reported to demonstrate elevated blood pressure (BP) measurements in the preschool time period [ 7, 8] there are limited published BP data for the pre-school offspring of women with GDM [ 9].
Complete management and health data for the gilts and their offspring were maintained.
This correction improved the estimation of allele frequencies in the current study from a correlation with the true data of r = 0.961 for the offspring pool to r = 0.997 when k correction was applied to that pool.
Class (5) probably had a high rate of true null alleles because we had data for multiple offspring and only included SNPs based on missing genotypes when at least five individuals had missing genotypes.
HAPO data for offspring at age 2 showed no relationship between offspring weight and maternal glycaemia level during pregnancy [ 19].
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