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This study illustrates the power of 2D NMR techniques to obtain detailed structural data for the interactions between two protein partners.
The data for the interactions between the PAH-type inducers and inhibitors clearly indicate a synergistic effect on embryotoxicity for coexposures to BNF + ANF, BaP + ANF, BNF + FL, and BNF + AA.
A large scale reconstruction of signalling networks relying on kinetic data has not yet appeared due to the lack of available kinetic data for the interactions in the network.
Interactions recorded for the SH2 domains of Gads and Grap are not useful for predicting interactions in other cell types but may be considered as supporting data for the interactions of the closely related Grb2 SH2 domain.
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a, SPR binding data for the interaction of WM-8014 wimmobilizedized KAT6A and KAT7 MYST domains.
a, SPR binding data for the interaction of WM-1119 wimmobilizedized KAT6A, KAT7 and KAT5, compared with the interaction of WM-8014.
Electronic structure methods provide data for the interaction of solutes with prismatic dislocation cores and basal dislocation cores.
We develop a geometry-based model from first-principles data for the interaction of solutes with a prismatic screw dislocation core, and predict the thermally activated cross-slip stress above room temperature in Mg alloys.
Quantitative experimental data for the interaction strength of graphene/substrate interface is very limited.
Surface plasmon resonance (SPR), which can monitor the formation and dissociation of the drug-protein complex in real-time and obtain the equilibrium (KD) and kinetic (kon and koff) data for the interaction, is one of the most excellent optical biosensor technologies [106 108].
A limitation of our model was the lack of data for the interaction between the APOE genotypes and each of the modifiable risk factors considered, which forced us to use a very approximate method to calculate the unknown interactions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com