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To obtain apo- and nucleosome-bound SWR1 data for refinement, we collected untilted cryo-NS data at liquid-nitrogen temperature and under low-dose conditions.
51 In order to obtain the corresponding P r), the theoretical SAXS intensity profile of the full-atom target structure obtained from Crysol is taken as input for Gnom which translates it into P r) which will be used as target data for refinement.
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We then conducted a priori data analysis with primary attention to the effects of multiple testing, followed by a posteriori data analysis for refinement of hypotheses and guidance of future work.
The data statistics for refinement are summarized in Table 1.
Diffraction data used for refinement of the Cg-Slx1-Slx4CCD3 structure were collected at 0.97626 Å.
Moreover, an adaptive short-term scheduling mechanism is employed, using monitoring data for the refinement of production schedules based on the current and future conditions of the shop-floor.
The amplitudes and phases of these structural factors were used as pseudo-experimental diffraction data for model refinement in Phenix.
This 3D model (available as Supplementary data) could be used as C1-dictionary data for structural refinement, protein docking or structure-based design.
Our study provides compelling data for further refinement of the Leishmania Antigen Detect™ ELISA for deployment in endemic regions for multiple VL management purposes.
Hence, data for structural refinement that were collected at a wavelength of 1.0000 Å yielded an appreciable anomalous signal for Zn.
This integrated model serves as a platform for applying many gene-centric extensions to FBA, including algorithms that incorporate "omics" data for model refinement.
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